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基于深度学习的超声层析成像低频扩展方法

A deep learning method for low-frequency expansion in ultrasound tomography

  • 摘要: 在基于全波反演的超声层析成像中, 由于常规医学超声探头频率大于1 MHz, 低频数据不足, 导致传统算法难以重建高质量图像。为此, 提出一种用于超声扫描数据低频扩展的深度学习方法, 通过预测缺失的低频信号, 改善全波反演的成像精度。设计并搭建超声带宽扩展网络(UBE-Net), 实现从探测器采集的宽带超声信号到低频扩展后信号的端到端映射。利用公开仿真数据集和自建的仿体数据集训练网络, 并分别在仿真、仿体和在体数据集上测试网络性能。实验结果表明, 所提方法能够有效增强探测器测量信号中的低频成分。在仿真和仿体实验中, 频带扩展后的信号信噪比分别高于25 dB和22 dB, 归一化均方误差均小于0.07。采用频带扩展后的超声信号进行全波反演, 能够有效改善重建的声速分布图质量。仿真和仿体实验中, 声速分布图的峰值信噪比至少可达34 dB和29 dB, 结构相似性指数均高于0.81。对在体数据集的测试表明, 重建的声速分布图的自然图像质量评估指数低于5.3, 无参考结构性相似性指数高于0.79。

     

    Abstract: In ultrasound tomography based on full-waveform inversion (FWI), the lack of low-frequency data, due to the conventional medical ultrasound probes having frequencies greater than 1 MHz, makes it difficult for traditional algorithms to reconstruct high-quality images. This paper proposes a deep learning approach for low-frequency extension of ultrasound tomographic scan data, which improves the reconstruction accuracy of FWI by predicting the missing low-frequency signals. An ultrasonic bandwidth expansion network (UBE-Net) is designed and implemented to achieve an end-to-end mapping from the broadband ultrasound signals collected by the detector to the low-frequency extended signals. The network was trained using publicly available simulated datasets and our own phantom datasets, and its performance was tested on simulated, phantom, and in vivo datasets. Experimental results demonstrate that the proposed method effectively enhances the low-frequency components of the detector data, with the signal-to-noise ratio (SNR) of the band-extended signals being higher than 25 dB and 22 dB in simulated and phantom experiments, respectively, and the normalized mean square error being less than 0.07. Using the band-extended ultrasound data for FWI significantly improves the quality of the reconstructed acoustic velocity distribution maps. In simulated and phantom experiments, the peak signal-to-noise ratio of the acoustic velocity distribution maps reached at least 34 dB and 29 dB, respectively, and the structural similarity index was higher than 0.81. Tests on in vivo datasets indicate that the natural image quality evaluator of the reconstructed acoustic velocity distribution maps is below 5.3, and the no-reference structural similarity is higher than 0.79.

     

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